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Cholestyramine for kidney stones

Healthwise
By Monica Rhodes

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Examples

Brand Name Chemical Name
Questran

How It Works

Cholestyramine attaches to bile in the intestine, which limits how much oxalate your intestines absorb. This reduces the amount of oxalate found in the urine and reduces the risk of forming kidney stones.

Why It Is Used

Cholestyramine is used in people with high levels of oxalate, especially those who also have inflammatory bowel disease (IBD).

How Well It Works

Taking cholestyramine along with drinking more fluids and eating fewer high-oxalate foods may prevent kidney stones. Foods high in oxalate include dark green vegetables, rhubarb, chocolate, tea and colas, wheat bran, nuts, cranberries, beans, and coffee.

Side Effects

The side effects of cholestyramine include:

  • Constipation.
  • Abdominal (stomach) pain.
  • Gas.
  • Heartburn.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

People with inflammatory bowel disease (IBD) may be able to reduce their risk of forming kidney stones by taking cholestyramine.

Cholestyramine is more commonly used to help lower the amount of cholesterol in the blood to reduce the risk of heart disease.

Complete the new medication information form (PDF)Click here to view a form.(What is a PDF document?) to help you understand this medication.

Credits

Author Monica Rhodes
Editor Kathleen M. Ariss, MS
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Kathleen Romito, MD - Family Medicine
Specialist Medical Reviewer Philip Belitsky, MD, FRCSC - Urology
Last Updated May 30, 2007
Last Updated: 05/30/2007