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Opioids for restless legs syndrome

Healthwise
By Kathe Gallagher, MSW; Cynthia Tank

Examples

Brand Name Chemical Name
Phenaphen with codeine, Tylenol with codeine
Anexsia, Lorcet, Tylox, Vicodin
Percodan
Darvon
Ultram

How It Works

Opioids are narcotics and are usually used to relieve pain. It is not known how these medications relieve symptoms of restless legs syndrome.

Why It Is Used

Opioids are usually used for restless legs syndrome only when other drugs have not relieved symptoms. A doctor will usually prescribe only a small amount initially to see whether it helps.

How Well It Works

Low doses of opioids are sometimes used on an as-needed basis to treat symptoms that appear irregularly.

Side Effects

Dizziness, sedation, nausea, vomiting, and constipation are the major side effects of opioids. Addiction or a tolerance can develop.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

More study is needed to discover the full range of side effects. Opioids have not yet been reviewed by the U.S. Food and Drug Administration specifically for treatment of restless legs syndrome.

Complete the new medication information form (PDF)Click here to view a form.(What is a PDF document?) to help you understand this medication.

Credits

Author Kathe Gallagher, MSW
Author Cynthia Tank
Editor Alison Allen
Editor Kathleen M. Ariss, MS
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Adam Husney, MD - Family Medicine
Specialist Medical Reviewer Wayne A. Hening, MD - Neurology
Specialist Medical Reviewer Karin M. Lindholm, DO - Neurology
Last Updated April 4, 2007
Last Updated: 04/04/2007

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