Hypomelanosis of Ito

Synonyms

• HMI
• Incontinenti Pigmenti Achromians
• IPA
• ITO Hypomelanosis
• ITO

Disorder Subdivisions

• None

General Discussion

Hypomelanosis of Ito (HI) is a rare disorder that is distinguished by a lack of skin color (hypopigmentation) affecting many areas of the body. The defect in skin color is likely to appear as streaks, patches, or whorls. It is often associated with other symptoms such as intellectual and developmental retardation, seizures (neurological anomalies), ocular, skeletal and dental problems and/or a small head. The diagnosis is sometimes difficult due to the number and variety of other conditions that may be present and confuse the situation. Most cases of HI are not the result of an inherited defect, although some cases are inherited as an autosomal dominant trait.
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Resources

National Foundation for Ectodermal Dysplasias
410 East Main Street
PO Box 114
Mascoutah, IL 62258-0114
Tel: (618)566-2020
Fax: (618)566-4718
Email: info@nfed.org
Internet: http://www.nfed.org

March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
Tel: (914)428-7100
Fax: (914)997-4763
Tel: (888)663-4637
Email: Askus@marchofdimes.com
Internet: http://www.marchofdimes.com

NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
1 AMS Circle
Bethesda, MD 20892-3675
USA
Tel: 3014954484
Fax: 3017186366
Tel: 8772264267
TDD: 3015652966
Email: NIAMSinfo@mail.nih.gov
Internet: http://www.niams.nih.gov

HITS (UK) (Family Support Network)
C/O Terri Grant
Saskatchewan
99 Great Cambridge Rd
London, Intl N17 7LN
United Kingdom
Tel: (44) 7940 114943
Fax: (44) 208 352 1824
Email: tgrant@hitsuk.freeserve.co.uk
Internet: http://www.e-fervour.com/hits

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated: 7/8/2002
Copyright 1993, 1996, 2002 National Organization for Rare Disorders, Inc.