Synonyms

• Familial Continuous Skin Peeling
• Skin Peeling Syndrome
• Deciduous Skin
• Keratolysis Exfoliativa Congenita

Disorder Subdivisions

• Acral Peeling Skin Syndrome

General Discussion

Peeling skin syndrome is an extremely rare inherited disorder characterized by continual, spontaneous skin peeling (exfoliation). Other findings may include reddening of the skin (erythema) and itching (pruritus). At least one group working on this disorder distinguishes between a non-inflammatory form called type A and an inflammatory form known as type B. Type B is associated with congenital erythroderma, a condition in which the skin has an intense red color. There is mounting evidence that the inflammatory type B is a variant of Netherton syndrome.

Based on its occurrence in families in which husband and wife are close relatives, peeling skin syndrome is likely to be transmitted as an autosomal recessive genetic trait.

Resources

Foundation for Ichthyosis & Related Skin Types
1364 Welsh Road G2
North Wales, PA 19454
Tel: (215)619-0670
Fax: (215)619-0780
Tel: (800)545-3286
Email: info@scalyskin.org
Internet: http://www.scalyskin.org

NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
1 AMS Circle
Bethesda, MD 20892-3675
USA
Tel: 3014954484
Fax: 3017186366
Tel: 8772264267
TDD: 3015652966
Email: NIAMSinfo@mail.nih.gov
Internet: http://www.niams.nih.gov/Health_Info

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. ® (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see http://www.rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  5/1/2008
Copyright  1988, 1989, 1992, 1993, 1997, 1998, 2005, 2006National Organization for Rare Disorders, Inc.