Skin cancer, melanoma: Prevention - Patient Information [NCI PDQ]

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Skin Cancer Prevention (PDQ®)

Overview of Prevention

Prevention

Doctors cannot always explain why one person gets cancer and another does not. However, scientists have studied general patterns of cancer in the population to learn what things around us and what things we do in our lives may increase our chance of developing cancer.

Anything that increases a person’s chance of developing a disease is called a risk factor; anything that decreases a person’s chance of developing a disease is called a protective factor. Some of the risk factors for cancer can be avoided, but many cannot. For example, although you can choose to quit smoking, you cannot choose which genes you have inherited from your parents. Both smoking and inheriting specific genes could be considered risk factors for certain kinds of cancer, but only smoking can be avoided. Prevention means avoiding the risk factors and increasing the protective factors that can be controlled so that the chance of developing cancer decreases.

Although many risk factors can be avoided, it is important to keep in mind that avoiding risk factors does not guarantee that you will not get cancer. Also, most people with a particular risk factor for cancer do not actually get the disease. Some people are more sensitive than others are to factors that can cause cancer. Talk to your doctor about methods of preventing cancer that might be effective for you.

Purposes of this summary

The purposes of this summary on skin cancer prevention are to:

• Give information on skin cancer and how often it occurs.
• Describe skin cancer prevention methods.
• Give current facts about which people or groups of people would most likely be helped by following skin cancer prevention methods.

You can talk to your doctor or health care professional about cancer prevention methods and whether they would be likely to help you.

Skin Cancer Prevention

The skin protects the body against heat and light, injury, and infection. It also helps regulate body temperature, stores water and fat, and produces vitamin D. The skin is the body’s largest organ and is made up of two main layers: the outer epidermis and the inner dermis.

There are 3 types of skin cancer: basal cell carcinoma, squamous cell carcinoma (together referred to as nonmelanoma skin cancer), and melanoma. The outer layer of the skin is made up of squamous cells. Basal cells are found below the squamous cells. Melanocytes are in the deepest layer of epidermis. Melanoma develops from melanocytes.

Significance of skin cancer

Skin cancer is the most commonly occurring cancer in the United States. Basal cell carcinoma and squamous cell carcinoma (nonmelanoma skin cancer) are the most common forms of skin cancer, but are easier to cure than melanoma. The number of new cases of skin cancer appears to be increasing each year. The number of deaths due to skin cancer, however, is fairly small.

Skin cancer prevention

NONMELANOMA SKIN CANCER (BASAL CELL CARCINOMA AND SQUAMOUS CELL CARCINOMA): Studies have suggested that reducing exposure to ultraviolet (UV) radiation decreases the incidence of nonmelanoma skin cancer. Ultraviolet radiation is a stream of invisible high-energy rays coming from the sun. Artificial sources such as tanning booths and sunlamps also produce ultraviolet radiation.

Sun exposure can be reduced by changing patterns of outdoor activities to reduce time of exposure to high-intensity UV radiation (the sun is strongest from 11 am to 3 pm), wearing protective clothing (such as long sleeves and hats) when exposed to sunlight, and by using adequate amounts of sufficiently protective sunscreen.

It is not known whether using sunscreen lowers the risk of either squamous cell carcinoma or basal cell carcinoma.

People whose skin tans poorly or burns easily after sun exposure are particularly susceptible to nonmelanoma skin cancer. These people in particular may benefit by following prevention methods for nonmelanoma skin cancer.

MELANOMA: It is not known if avoiding sunburns reduces a person's chance of developing melanoma skin cancer.

Sunburn can be avoided by changing patterns of outdoor activities to reduce time of exposure to high-intensity UV radiation (the sun is strongest from 11 am to 3 pm), wearing protective clothing (such as long sleeves and hats) when exposed to sunlight, and using sunscreen.

Sunscreen is not a substitute for avoidance of sun exposure.

People whose skin tans poorly or who have a large number of abnormal moles may have an increased risk of developing melanoma skin cancer. These people in particular may benefit by following prevention methods for melanoma.

Changes to This Summary (07/20/2006)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Changes were made to this summary to match those made to the health professional version.

Questions or Comments About This Summary

If you have questions or comments about this summary, please send them to Cancer.gov through the Web site’s Contact Form. We can respond only to email messages written in English.

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About PDQ

PDQ IS A COMPREHENSIVE CANCER DATABASE AVAILABLE ON NCI'S WEB SITE.

PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site. PDQ is provided as a service of the NCI. The NCI is part of the National Institutes of Health, the federal government's focal point for biomedical research.

PDQ CONTAINS CANCER INFORMATION SUMMARIES.

The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries are available in two versions. The health professional versions provide detailed information written in technical language. The patient versions are written in easy-to-understand, nontechnical language. Both versions provide current and accurate cancer information.

THE PDQ CANCER INFORMATION SUMMARIES ARE DEVELOPED BY CANCER EXPERTS AND REVIEWED REGULARLY.

Editorial Boards made up of experts in oncology and related specialties are responsible for writing and maintaining the cancer information summaries. The summaries are reviewed regularly and changes are made as new information becomes available. The date on each summary ("Date Last Modified") indicates the time of the most recent change.

PDQ ALSO CONTAINS INFORMATION ON CLINICAL TRIALS.

A clinical trial is a study to answer a scientific question, such as whether a certain drug or nutrient can prevent cancer. Trials are based on past studies and what has been learned in the laboratory. Each trial answers certain scientific questions in order to find new and better ways to help cancer patients and those who are at risk for cancer. During prevention clinical trials, information is collected about the effects of a new prevention method and how well it works. If a clinical trial shows that a new method is better than one currently being used, the new method may become "standard." People who are at high risk for a certain type of cancer may want to think about taking part in a clinical trial.

Listings of clinical trials are included in PDQ and are available online at NCI's Web site. Descriptions of the trials are available in health professional and patient versions. Many cancer doctors who take part in clinical trials are also listed in PDQ. For more information, call the Cancer Information Service 1-800-4-CANCER (1-800-422-6237); TTY at 1-800-332-8615.

Date Last Modified: 2006-07-20

If you want to know more about cancer and how it is treated, or if you wish to know about clinical trials for your type of cancer, you can call the NCI's Cancer Information Service at 1-800-422-6237, toll free. A trained information specialist can talk with you and answer your questions.