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Risk factors for cervical cell changes

Healthwise
By Sandy Jocoy, RN

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Factors that increase the risk of cervical cell changes (dysplasia) that can cause an abnormal Pap test include:

  • Being infected with certain high-risk types of the human papillomavirus (HPV).
  • Being infected with the human immunodeficiency virus (HIV).
  • Smoking or having a history of smoking.
  • Sexual intercourse with a partner who is infected with HPV.
  • Starting sexual intercourse at an early age (before age 18).
  • Having three or more sex partners in a lifetime.
  • Having sexual intercourse with someone who has had multiple sex partners.
  • Using birth control pills. Studies have shown that women who use birth control pills for many years have an increased risk of cervical cell changes.
  • Having an impaired immune system.
  • Having multiple full-term pregnancies (high parity).
  • Exposure to diethylstilbestrol (DES) in utero, though this is rare.

Credits

Author Sandy Jocoy, RN
Editor Kathleen M. Ariss, MS
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Joy Melnikow, MD, MPH - Family Medicine
Specialist Medical Reviewer Kevin Holcomb, MD - Gynecologic Oncology
Last Updated January 5, 2009
Last Updated: 01/05/2009