Cause
The exact cause of uterine fibroids is not known. Fibroids begin when cells overgrow in the muscular wall of the uterus.
After a fibroid develops, the hormones estrogen and progesterone appear to influence its growth.1 A woman's body produces the highest levels of these hormones during her childbearing years. After menopause, when hormone levels decline, fibroids usually shrink or disappear.
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