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Effects of exposure to diethylstilbestrol (DES)

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By Sandy Jocoy, RN

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Between 1948 and 1971, millions of women took a drug called diethylstilbestrol (DES) to prevent miscarriage.

Daughters born to women who took DES while pregnant have a slightly higher risk of developing:

  • Abnormal cervical cells that cause an abnormal Pap test result.
  • Cancer of the vagina.
  • Structural problems in the reproductive organs (such as a T-shaped uterus), which can cause infertility.

Credits

Author Sandy Jocoy, RN
Editor Kathleen M. Ariss, MS
Associate Editor Pat Truman, MATC
Primary Medical Reviewer Joy Melnikow, MD, MPH - Family Medicine
Specialist Medical Reviewer Kevin Holcomb, MD - Gynecologic Oncology
Last Updated January 5, 2009
Last Updated: 01/05/2009

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