What Increases Your Risk
Diabetes is the most common cause of nephrotic syndrome in adults in the United States. About one-third of children who develop nephrotic syndrome have diabetes.
You also have an increased risk of developing nephrotic syndrome if you have a disease that results in an impaired immune system, such as AIDS or lupus.
Nephrotic syndrome is a relatively rare disease that can occur at any age. In the United States, it affects between 2 and 7 people out of 100,000 each year. Children most commonly affected are between the ages of 18 months and 8 years. Boys are affected more often than girls.1
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