Buprenorphine for drug dependence

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Examples

Brand Name Chemical Name
Subutex buprenorphine
Suboxone buprenorphine and naloxone

You take buprenorphine by placing pills under your tongue.

How It Works

Buprenorphine is an opioid medicine similar to morphine, codeine, and heroin. It targets the same places in the brain that opioids do. It relieves drug cravings without giving you the same high as other opioid drugs.

Buprenorphine can cause side effects similar to other opioids and also can cause physical dependence.

Why It Is Used

Buprenorphine can help treat addiction to opioid drugs, including heroin and narcotic painkillers. It prevents or reduces withdrawal symptoms caused by quitting these drugs.

How Well It Works

Research has shown that buprenorphine is effective for treating opioid addiction.1

Side Effects

Buprenorphine or buprenorphine and naloxone may cause side effects. Tell your doctor if any of the following side effects are severe or do not go away:

  • Belly pain
  • Constipation
  • Headache
  • Sleep problems
  • Sweating
  • Vomiting

Other side effects are less common. Call your doctor if you have any of the following side effects:

  • Flu-like symptoms
  • Hives, itching, or a skin rash
  • Lack of energy or extreme tiredness
  • Pain in the upper right part of your belly
  • Slowed breathing
  • Trouble breathing or swallowing
  • Unusual bleeding or bruising
  • Upset stomach or loss of appetite
  • Yellowing of the skin or eyes

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Do not take mood-altering drugs, narcotic painkillers, sedatives, sleeping pills, or tranquilizers while taking buprenorphine.

In some cases, buprenorphine may be used as an alternative to methadone, which also is given to treat opioid addiction. Buprenorphine may have less severe side effects than methadone. Talk to your doctor about what might work best for you.

Complete the new medication information form (PDF)Click here to view a form.(What is a PDF document?) to help you understand this medication.

References

Citations

  1. Buprenorphine: An alternative to methadone (2003). Medical Letter on Drugs and Therapeutics, 45(W1150A): 13–15.

Credits

Author Paul Lehnert
Author Ryan Powers
Editor Roya Camp
Editor Katy E. Magee, MA
Associate Editor Terrina Vail
Primary Medical Reviewer Adam Husney, MD
- Family Medicine
Specialist Medical Reviewer James R. McKay, PhD
- Psychology
Last Updated February 15, 2008
Author:Paul Lehnert
Ryan Powers
Medical Review:Adam Husney, MD - Family Medicine
James R. McKay, PhD - Psychology
Last Updated: 02/15/2008

© 1995-2007, Healthwise, Incorporated, P.O. Box 1989, Boise, ID 83701. ALL RIGHTS RESERVED.

This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information. For more information, click here. Privacy Policy. How this information was developed.

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