Oxcarbazepine

[ Pronunciation: ox kar BAY zeh peen ]
Brand Names: Trileptal
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What is the most important information I should know about oxcarbazepine?

donot Do not take this medication if you are allergic to oxcarbazepine or to a similar medicine called carbamazepine (Carbatrol, Tegretol).

Before taking oxcarbazepine, tell your doctor if you have liver or kidney disease.

nopreg Do not use this medication without your doctor's consent if you are pregnant. It could cause harm to the unborn baby. Oxcarbazepine should not be used during pregnancy, but taking the medicine can make birth control pills less effective. Use a non-hormone method of birth control (not birth control pills) to prevent pregnancy while you are taking oxcarbazepine. Tell your doctor if you become pregnant during treatment.

Oxcarbazepine can reduce the sodium in your body to dangerously low levels, which can cause a life-threatening electrolyte imbalance. Contact your doctor right away if you have nausea with vomiting, weakness, headache, confusion, mood changes, and/or increased or more severe seizures.

You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

emt Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

There are many other medicines that can interact with oxcarbazepine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What is oxcarbazepine?

Oxcarbazepine is in a group of drugs called anticonvulsants, or antiepileptic drugs. It works by decreasing nerve impulses that cause seizures.

Oxcarbazepine is used to treat partial seizures in adults and children who are at least 2 years old.

Oxcarbazepine may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking oxcarbazepine?

donot Do not take this medication if you are allergic to oxcarbazepine or to a similar medicine called carbamazepine (Carbatrol, Tegretol).

Before taking oxcarbazepine, tell your doctor if you have liver or kidney disease. If you have any of these conditions you may not be able to use oxcarbazepine, or you may require a dose adjustment or special tests during treatment.

You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

nopreg FDA pregnancy category D. This medication can cause harm to an unborn baby. Oxcarbazepine should not be used during pregnancy, but taking the medicine can make birth control pills less effective. Use a non-hormone method of birth control (not birth control pills) to prevent pregnancy while you are taking oxcarbazepine. Tell your doctor if you become pregnant during treatment.
nobrfeed Oxcarbazepine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
nochild Do not give this medication to a child younger than 2 years old.

How should I take oxcarbazepine?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from this medication.

water Take oxcarbazepine with a full glass of water.
shake Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, use the oral dosing syringe provided with this medicine. If you did not receive an oral syringe with your medication, ask your pharmacist for one.

Give the oral liquid directly from the oral syringe, or mix the medicine with a small glass of water. After using the syringe, rinse it with water and allow it to air dry.

donot Do not stop taking the medication even if you feel better. It is important to take oxcarbazepine regularly to prevent seizures from recurring. Get your prescription refilled before you run out of medicine completely. Call your doctor promptly if this medicine does not seem to be working as well in preventing your seizures.
emt Carry an ID card or wear a medical alert bracelet stating that you are taking oxcarbazepine, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you have a seizure disorder.

Seizures are often treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

rt Store oxcarbazepine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

emt Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of an oxcarbazepine overdose are unknown.

What should I avoid while taking oxcarbazepine?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

dizzy Oxcarbazepine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
noalcohol Do not drink alcohol while taking oxcarbazepine. Alcohol may increase drowsiness caused by oxcarbazepine. It may also increase the risk of seizures.

What are the possible side effects of oxcarbazepine?

emt Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Oxcarbazepine can reduce the sodium in your body to dangerously low levels, which can cause a life-threatening electrolyte imbalance. Contact your doctor right away if you have nausea, vomiting, weakness, thirst, loss of appetite, headache, confusion, hallucinations, muscle pain or weakness, and/or increased or more severe seizures.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

emt Call your doctor at once if you have any of these serious side effects:
  • sore throat, and headache with a severe blistering, peeling, and red skin rash;
  • jaundice (yellowing of the skin or eyes);
  • fever, swollen glands, flu-like symptoms;
  • easy bruising or bleeding, unusual weakness;
  • urinating less than usual or not at all; or
  • increased seizures.

Less serious side effects may include:

  • mild nausea, vomiting, stomach pain, diarrhea;
  • problems with speech, balance, or coordination;
  • blurred vision;
  • mental slowness, trouble concentrating;
  • tremors or shaking;
  • dizziness, drowsiness; or
  • skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect oxcarbazepine?

Before using oxcarbazepine, tell your doctor about all other seizure medications you are taking, including:

  • carbamazepine (Carbatrol, Tegretol);
  • phenobarbital (Luminal, Solfoton);
  • phenytoin (Dilantin); or
  • valproic acid (Depakene).

There are many other medicines that can interact with oxcarbazepine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?

Your pharmacist has information about oxcarbazepine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others and use this medication only for the condition prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2003 Cerner Multum, Inc. Version: 5.04. Revision date: 03/13/2008.

Last Updated: 03/13/2008

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