Depression, extreme mood or personality changes, or episodes of intense or unusually high energy seen in bipolar disorder can be caused by many disorders. Other possible causes for these types of symptoms include:

• Drug, alcohol, or other substance abuse.
• Schizophrenia.
• Depression.
• Attention deficit hyperactivity disorder (ADHD).
• Hypothyroidism or hyperthyroidism.
• Psychosis from steroid use.

It is also possible that certain serious medical conditions, such as a brain tumor, can cause a change in personality or behavior. You or your loved one should seek treatment for these symptoms. Be sure to discuss all your symptoms with your doctor to help in making an accurate diagnosis.