Lithium carbonate for schizophrenia

Sometimes lithium carbonate (Lithobid, Lithane, Eskalith) is added to other medicines to treat schizophrenia. It is not clear exactly how lithium works, but it may help regulate certain brain chemicals (neurotransmitters) that cause mood changes. Lithium carbonate may be most helpful for treating the mood problems associated with schizophrenia, such as depression.

Common side effects of lithium carbonate include:

• Nausea.
• Diarrhea.
• Loss of appetite, feeling of fullness or swollen stomach, and/or stomach upset.
• Dry mouth, increased thirst, and increased urination.
• Headache, slight memory loss, or confusion.
• Sensitivity to cold.
• Tiredness and sleepiness.
• Weight gain.
• Slight hand tremor.

Lithium carbonate is a salt and acts like other salts (such as sodium) in the body. Any change in the balance between body salts and liquids (mostly water) in the body can change the amount of lithium carbonate in the blood. Lithium carbonate blood levels need to be kept within a safe range. Levels that are high can cause serious side effects, even death. Levels that are low can cause symptoms of mood swings or emotional instability. You will need to learn how to keep lithium carbonate blood levels at a safe and effective level and to recognize the signs of high lithium carbonate. It is very important to have your blood tested regularly (from every week to every 6 or 12 months) to check lithium carbonate blood levels.

You also need to be aware of the following:

• Because lithium carbonate may make you tired and less alert, avoid driving a car or using other dangerous machinery until you know how lithium affects you.
• Always seek care from a health professional if you are a woman and become pregnant while taking lithium carbonate. Women who take lithium carbonate and breast-feed their babies also need medical care from a health professional.
• Do not drink alcohol if you are taking lithium carbonate. Lithium can hide the signs of alcohol intoxication; your blood alcohol levels could become dangerously high if you drink while taking this medicine.
• Lithium carbonate can affect thyroid and kidney function. Your doctor may have your blood tested to monitor thyroid and kidney function while you are taking lithium.
• Always seek medical treatment if you notice signs of excess lithium in the blood. Always tell each health professional who treats you that you are taking lithium carbonate. Taking certain medicines can interfere with the amount of lithium in your blood. Some medicines can cause your lithium blood level to get too high, and other medicines can cause it to get too low.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)