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Should I use injections for erection problems?

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By Monica Rhodes

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Introduction

This information will help you understand your choices, whether you share in the decision-making process or rely on your doctor's recommendation.

Key points in making your decision

An erection problem is not a life-threatening condition, yet it can seriously affect your emotional health and sense of self-worth. It can also make it difficult to father a child, if that is your desire. So the decision about whether to treat an erection problem is often based on your and your partner's preferences. Consider the following when making your decision:

  • If you are able to try phosphodiesterase-5 inhibitors (such as sildenafil [Viagra], tadalafil [Cialis], and vardenafil [Levitra]) but have not, you should try one of these medicines first.
  • At this time, it is not known how effective injections are in those who have already tried phosphodiesterase-5 inhibitors.

Medical Information

What is an erection problem?

An erection problem (also called erectile dysfunction and sometimes impotence) refers to a man's consistent inability to get or maintain an erection sufficient to have satisfactory sex. It does not mean a lack of sexual interest or desire or the occasional difficulty achieving or maintaining an erection that affects all men at some time in their lives.

What causes an erection problem?

The cause of erection problems may be physical (such as injury to the nerves or loss of blood flow going to the penis) or psychological (such as anxiety or depression). Medications you take for other conditions, alcohol consumption, smoking, and illegal drug use can cause erection problems.

Certain conditions may affect blood flow or the nervous system, increasing the risk of having erection problems. These include diabetes, high blood pressure, high cholesterol levels, atherosclerosis, multiple sclerosis, and Parkinson's disease.

Erection problems can occur at any age but are more common in older men, who often have additional health problems or who may be taking medicines that can interfere with normal erectile function. Treatment of erection problems in older men can be as effective as in younger men.

Why treat an erection problem?

The decision about whether to treat an erection problem may not be as straightforward as the decision about whether to treat many other medical conditions. An erection problem is not life-threatening, yet it can seriously affect your emotional health and sense of self-worth. It can also make it difficult to father a child, if that is your desire. So the decision about whether to treat an erection problem is often based on personal preference.

Very often, this decision is also based on how intensive or invasive the treatment is and its chance of succeeding. Injecting medication directly into the penis is often effective, but it is usually only considered after oral medicines (such as sildenafil [Viagra], tadalafil [Cialis], and vardenafil [Levitra]) have been tried.

Your Information

Your choices are:

  • Try MUSE (medicated urethral system for erections), which calls for inserting a tiny pellet of alprostadil into the opening at the end of the penis (the urethra). A thin tube contains the pellet of medicine. The tube is inserted into the opening in the end of the penis. By pressing a button on the applicator, the pellet is released into the penis.
  • Inject medication into the side of the penis. This often involves using a mixture of medicines that include alprostadil (Caverject), papaverine hydrochloride (Pavabid), and phentolamine mesylate (Regitine).
  • Try counseling or sex therapy.
  • Seek other ways to express intimacy.

The decision about whether to use injections or pellets takes into account your personal feelings and the medical facts.

Deciding about medications for erection problems
Medication Reasons to use for an erection problem Reasons not to use for an erection problem

MUSE

  • About 6 out of 10 men using MUSE achieve erections sufficient for intercourse. But smaller doses have smaller percentages of positive results.1
  • Erection develops in about 10 minutes and lasts 30 minutes to an hour or longer.
  • MUSE does not usually cause bruising or scar tissue (as injections may).
  • The medicine causes severe pain.
  • The tube used to insert the medicine causes mild injury to the urethra, such as a scrape that causes a small drop of blood at the tip of the urethra.
  • The medicine can cause pain and irritation in your partner's vagina when you ejaculate.
  • Your partner cannot perform oral sex while you are using this medicine.

Injections into the side of the penis

  • Up to 90% of men using this method achieve erections sufficient for sexual intercourse.2
  • Erection lasts 30 minutes to an hour or longer.
  • Dose can be adjusted to create an erection that lasts the desired length of time
  • Auto-injector is available if unable to give standard injections.
  • Injections can bruise the penis.
  • Injections can cause mild to moderate pain in the penis.
  • Repeated injections can lead to scar tissue in the penis (fibrosis).

Following are some general considerations about using injections or pellets for an erection problem.

Considerations about medications for erection problems
Reasons to consider injections or pellets for an erection problem Reasons not to consider injections or pellets for an erection problem
  • Enhanced self-esteem because of your ability to have intercourse
  • Fulfills the need to show intimacy through sexual intercourse
  • You want to have children.

Are there other reasons you might want to use injections?

  • The idea of injecting a pellet into the opening of the penis or an injection into the side of the penis is not pleasant.
  • You must stop lovemaking to insert or inject the medicine into the penis.
  • The treatment is potentially expensive if insurance does not pay for it.
  • These methods are less likely to be effective in men whose blood flow into or out of the penis is severely impaired.
  • Injecting medicine into the penis may be difficult for men who have vision problems.

Are there other reasons you might not want to use injections?

These personal stories may be helpful in making your decision.

Wise Health Decision

Use this worksheet to help you make your decision. After completing it, you should have a better idea of how you feel about using injections or pellets for an erection problem. Discuss the worksheet with your doctor.

Circle the answer that best applies to you.

I have no vision problems that might make it difficult to use these medicines. Yes No Unsure
We have the finances and/or insurance to pay for the medicine and supplies. Yes No Unsure
Sexual intercourse is important to us. Yes No Unsure
Being able to have sexual intercourse will help my or my partner's self-esteem. Yes No Unsure
It would be inconvenient to have to stop our lovemaking to give an injection. Yes No Unsure
We can be intimate without having sexual intercourse. Yes No Unsure
We feel capable of giving an injection in the penis. Yes No Unsure

We worry about the side effects of medicine.

Yes No Unsure

Use the following space to list any other important concerns you have about this decision.

 

 

 

 

 

What is your overall impression?

Your answers in the above worksheet are meant to give you a general idea of where you stand on this decision. You may have one overriding reason to use or not use injections or pellets.

Check the box below that represents your overall impression about your decision.

Leaning toward using injections or pellets

 

Leaning toward NOT using injections or pellets

         

Return to the topic:

References

Citations

  1. Tharyan P, Gopalakrishanan G (2006). Erectile dysfunction, search date August 2006. Online version of BMJ Clinical Evidence. Also available online: http://www.clinicalevidence.com.

  2. Lue TF, Broderick GA (2007). Evaluation and nonsurgical management of erectile dysfunction and premature ejaculation. In AJ Wein, ed., Campbell-Walsh Urology, 9th ed., vol. 1, pp. 750–787. Philadelphia: Saunders Elsevier.

Credits

Author Monica Rhodes
Editor Kathleen M. Ariss, MS
Associate Editor Michele Cronen
Associate Editor Tracy Landauer
Associate Editor Pat Truman, MATC
Primary Medical Reviewer E. Gregory Thompson, MD - Internal Medicine
Specialist Medical Reviewer Christopher G. Wood, MD, FACS - Urology/Oncology
Last Updated May 21, 2008
Last Updated: 05/21/2008

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