Leriche's syndrome is the term used when the following symptoms related to peripheral arterial disease of the legs are present:

• Muscle wasting (atrophy) of the leg
• Buttock, thigh, or calf pain

Leriche's syndrome usually occurs in men and commonly also causes impotence (erectile dysfunction). Impotence is common in men with lack of adequate blood flow (arterial insufficiency). Blockages can decrease blood flow to the arteries that supply the penis.