How It Works
Procarbazine is classified as an alkylating agent. It causes cell death by interfering with the way genetic material (DNA) in the cell multiplies.
Why It Is Used
Procarbazine is used to treat leukemia and non-Hodgkin's lymphoma. It may also be used to treat other kinds of cancer.
Side Effects
Side effects of procarbazine are common, generally mild, and may include:
- Nausea or vomiting.
- Loss of appetite.
- Mouth sores (stomatitis).
- Changes in the way things taste.
- Cough or shortness of breath.
- Tingling or numbness of fingers or toes (peripheral neuropathy).
- Skin rash, which may itch.
- Diarrhea.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
Procarbazine should be administered only under the supervision of a medical oncologist or hematologist.
Procarbazine can affect your ability to have children. You may not be able to become pregnant or father a child after taking procarbazine. Discuss fertility with your doctor before starting treatment with this medication.
Procarbazine can cause birth defects. Do not use this medication if you are pregnant or wish to become pregnant or father a child while you are taking it.
Women who take this medication may experience menopausal symptoms, including hot flashes and vaginal dryness.
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Credits
| Author | Robin Parks, MS |
| Editor | Kathleen M. Ariss, MS |
| Associate Editor | Tracy Landauer |
| Associate Editor | Pat Truman |
| Associate Editor | Terrina Vail |
| Primary Medical Reviewer | Caroline S. Rhoads, MD - Internal Medicine |
| Specialist Medical Reviewer | Douglas A. Stewart, MD - Medical Oncology |
| Last Updated | June 12, 2006 |
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