How It Works
The exact way that an antihistamine may help with vertigo is not known. Some of these antihistamines may also reduce nausea and vomiting.
Dimenhydrinate and promethazine are available as an injection, suppository, or tablet. Diphenhydramine is available as an injection or a tablet.
Why It Is Used
Antihistamines may be prescribed to control vertigo that is caused by inner ear problems, including Ménière's disease, inflammation of the inner ear (labyrinthitis), benign paroxysmal positional vertigo (BPPV), and inflammation of the nerve to the inner ear (vestibular neuritis). Dimenhydrinate may be used to prevent and control nausea and vomiting caused by chemotherapy.
How Well It Works
These medicines do give some people relief from vertigo and nausea. But there is no scientific evidence to show that these medicines help with symptoms of vertigo.1
Side Effects
The most commonly reported side effect is drowsiness. Do not use a medicine that makes you drowsy if you will be driving or operating dangerous equipment.
Antihistamines may also cause blurred vision or a dry mouth.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
Most antihistamines should be avoided during early pregnancy, if possible.
Don't give antihistamines to your child unless you've checked with the doctor first.
Complete the new medication information form (PDF)
(What is a PDF document?) to help you understand this medication.
Credits
| Author | Monica Rhodes |
| Editor | Kathleen M. Ariss, MS |
| Associate Editor | Pat Truman, MATC |
| Primary Medical Reviewer | Anne C. Poinier, MD - Internal Medicine |
| Specialist Medical Reviewer | Colin Chalk, MD, CM, FRCPC - Neurology |
| Last Updated | December 29, 2008 |



