Midrin is a combination of the drugs isometheptene, acetaminophen, and dichloralphenazone. This drug combines properties of a pain reliever, a medicine that helps narrow (constrict) blood vessels, and a mild sedative to help reduce migraine headache pain.

Side effects of Midrin can include dizziness and a skin rash.

Midrin is a prescription medication that comes in tablet form. The usual adult dosage is 2 tablets taken together followed by 1 tablet every hour until your pain is relieved. You should not take more than 5 tablets within a 12-hour period.

You may not be able to use Midrin if you have glaucoma, renal disease, hypertension, certain heart problems, hepatic disease, or if you are taking a monoamine oxidase inhibitor (MAOI). Be sure to discuss with your doctor whether Midrin is right for you before you take this medication.