By Howard Levy, M.D. Provided by: Johns Hopkins University

Your Health Today

Medications for Depression - Part 2 By Howard Levy, M.D. - Posted Fri, Jan 09, 2009, 9:26 pm PST

Showing 1-4 of 4 Comments

Leave a Comment
  • 1. Posted by A Yahoo! Health User on Tue, Jan 13, 2009, 2:31 pm PST

    The Dr. took me off Paxil, The strongest available,dose at the time, "weaned" me off for two days and then put me on wellbutrin. With in 4 days that the DR put me on Wellbutrin, I did loose weight, still smoked, BUT did get very violent!!!!! REALLY wanted to commit succide OR kill anyone near me. I TOLD the Dr. that maybe I had to be off a little longer from the Paxil, a step down type of thing, like you do with Predisone,,,,,, This was all back in the early 90's, when I think that most did not know about the risks and benifits of SSR's. Anyways, I am now on CELEXA, 60mg. ( The most I can have they say for my weight,lbs160) Much happier. But remember, YOU STILL have to persavear!!!!!!! NO---- ONE OWNS YOU!!!! YOU DO P.S. IF you think your meds are just not working? PLEASE see your Dr/ one you trust and listens, ASK!

    Report Abuse
  • 2. Posted by A Yahoo! Health User on Fri, Jan 23, 2009, 10:28 pm PST

    Pharmacologically Enhancing Psychotropic Pharmaceuticals In the 1930s, physicians approached the mental illness of depression a bit differently that we do today. While acknowledging a likely cause of depression in one of their patients is often due to some great misfortune, they seemed to focus on what is called a complex. A complex is disturbances of ideas and impulses that are the cause of consistent habitual patterns of thought, feelings, and behavior. An example of this state of mind of one who is depressed is one who experiences an exaggerated or obsessive concern or fear. And the etiology for this mental disorder was often undefined. People react differently to life stressors in their life, so depression cannot be empirically determined. In the 1930s, psychotherapy such as cognitive therapy was recommended for treating the depressed patient, and not pharmacological therapy. Also considered for the depressed patient was positive lifestyle changes that would lessen the pain that the depression was causing them. Try and be grateful, they would tell their patient, as well as thankful and appreciative for whatever good may be in their life, and normally the depressed patient would eventually recover Times have changed since then. Presently, serotonin-enhancing drugs are the therapeutic regimens for those who are suspect of having a depressed state, or perhaps the patient simply asks for these types of drugs due to their perception that they are depressed. Furthermore, and remarkably, various other mood disorders one may have can be treated with these drugs, typically called SSRIs. What is remarkable is that the mood disorders which will be discussed later are subject to debate and have also been brought to the attention to so many others through disease awareness campaigns by the makers of these SSRI drugs. So mental flaws claimed to be relieved by SSRI drugs may not be the case at all. With depression, the most severe cognitive and behavioral malfunctions are expressed in what is called a major depressive disorder, which is also called clinical depression or major depression. Symptoms of this type of depression, which is the most concerning to health care providers in particular due to its severity, include decreased or flat affect, decreased interest in activities once enjoyable, self perceptions of worthiness, guilt, regret, helplessness, and hopeless by the sufferer, to name a few of the diagnostic features that may be present with one who has such a major depressive disorder. The disease has a vexing insistence on staying with the victim for a lengthy period of time- often continuing to progress symptomatically in severity and discomfort. This disease is very disabling, and cannot be lifted by one’s will, so all health care professionals likely agree that depression is a potentially serious condition with their patients. Suicidal ideation and attempts are associated with major depression. These SSRI drugs mentioned earlier are known by some health care providers as third generation anti-depressants. Such drugs, drugs that affect the mind, are called psychotropic medications. SSRIs also include a few drugs in this class that include the addition of a norepinephrine uptake inhibitor added to the SSRI in one capsule, and these drugs are referred to as SNRI medications. The combination of two different drugs has made them the top class of prescriptions for psychological misalignment. There are several available SSRIs presently, yet it is believed that only two SNRIs are available, which are Cymbalta and Effexor. Some consider these classes of meds, the serotonin enhancers in these medications, have been considered the next generation mood enhancers- after the benzodiazepine hype decades ago, which was followed by what were called trycyclic drugs for depression for some time. Furthermor

    Report Abuse
  • 3. Posted by A Yahoo! Health User on Mon, Feb 16, 2009, 9:16 am PST

    Hello! I have lived with OCD, panic-disorder, and dysthymia for over 30 years. My first tx was Imiprimine, in 1985, following my initial diagnosis. My symptoms left within 6 weeks and, although since then I have been on several different meds (they seem to lose their efficacy after about 3 to 5 years), I have been in remission for all but two major depressions. I realized I still had OCD symptoms recently, and always had, it was just that they were so ingrained in me I didn't take them for anything but "quirkiness". Anyway, my reason for writing is that I have had a major depressive episode for almost a year. My Dr. added 225mg of Effexor to my usual 80 mg of Paxil (taken for years), and last month I began to feel better. I doubt it was the Effexor. Well, this week, after much stress, my depression (uncontrollable crying, waking up crying, inability to get up) seems to be easing back and I am terrified. I have a new psychiatrist and am starting cog-beh. therapy in Mar. to address my residual OCD. But, as I said, I am terrified that the black, terrible depression of recent time is back. Any feedback, please? I am very scared. Thanks.

    Report Abuse
  • 4. Posted by A Yahoo! Health User on Wed, May 27, 2009, 1:49 am PDT

    thanks for continuing informations your giving me..it is very helpful to me because i am a broadcaster here in the philippines

    Report Abuse

Leave Your Comment

Comment Guidelines You must sign in to post a comment

Yahoo! Health Videos

My Health

help

Tip of the Day

Provided by: RealAgeDec 11, 2009

Having a stroke is a definite life crisis. But what if you could reduce the chances that it'll deadly?

Read More »

View All Tips »

Tell us what you think about Yahoo! Health - Send us your feedback