The American College of Physicians (ACP) recommends the following:¹

• When a person is tested for the purpose of preventing coronary artery disease, his or her total cholesterol level should be measured once. If the result is near a point at which treatment is needed, the person may need to be tested periodically.
• Testing for total cholesterol levels is not recommended for men younger than 35 or women younger than 45 unless their history or physical exam suggests a family history of high cholesterol or at least two other risk factors for coronary artery disease are present.
• When testing is done for the purposes of preventing coronary artery disease, checking a total cholesterol level is reasonable but not always needed for men 35 to 65 years of age and for women 45 to 65 years of age.
• There is not enough evidence to either recommend or discourage testing for the purposes of preventing coronary artery disease in men and women 65 to 75 years of age.
• Testing is not recommended for men and women 75 years of age and older.
• All people who have coronary artery disease, have had a stroke, or are at high risk for coronary artery disease should have a lipoprotein analysis or at least a measurement of total and HDL cholesterol levels.