Cause
The cause of bladder cancer is not known. Changes in the genetic material (DNA) of bladder cells may play a role.
Bladder cancer is twice as likely to develop in smokers than in nonsmokers. Experts believe that smoking causes about half of bladder cancer in men and more than one-fourth of bladder cancer in women.1
Exposure to chemicals and other substances at work—including dyes, paints, leather dust, and others—may also cause bladder cancer.1, 2
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