| WHO* Dysplasia System | Cervical Intraepithelial Neoplasia (CIN) | The Bethesda System |
|---|---|---|
Normal (benign) |
Normal (benign) |
Normal (benign) |
Benign with inflammation |
Not reported in CIN |
Infection and atypical squamous cells (ASC), which includes ASC of undetermined significance (ASC-US) and ASC that cannot exclude high-grade squamous intraepithelial lesions (HSIL) (ASC-H) |
Dysplasia (mild) |
CIN 1 |
Low-grade squamous intraepithelial lesions (LSIL) |
Dysplasia (moderate to severe) |
CIN 2, CIN 3 |
High-grade squamous intraepithelial lesions (HSIL) |
Carcinoma in situ |
CIN 3 |
High-grade squamous intraepithelial lesions (HSIL) |
Invasive cancer |
Invasive cancer |
Squamous cell cancer |
* World Health Organization
Credits
| Author | Sandy Jocoy, RN |
| Editor | Kathleen M. Ariss, MS |
| Associate Editor | Pat Truman, MATC |
| Primary Medical Reviewer | Joy Melnikow, MD, MPH - Family Medicine |
| Specialist Medical Reviewer | Kevin Holcomb, MD - Gynecologic Oncology |
| Last Updated | January 5, 2009 |
Author:Sandy Jocoy, RN
Last Updated: 01/05/2009
