Hemolytic anemia is an inadequate amount of red blood cells, caused by the rapid destruction of red blood cells in the blood or spleen. Symptoms of hemolytic anemia may include fever, chills, shortness of breath, and a rapid heart rate.

Infection, some medications and other substances, and certain inherited diseases (such as sickle cell disease) can cause hemolytic anemia. Treatment for hemolytic anemia varies depending on the cause.