Cyclosporine for psoriasis

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Examples

Solution or capsule taken by mouth (oral), or solution taken as a shot (injection)

Brand Name Chemical Name
Sandimmune cyclosporine

The dosage of cyclosporine depends on your body weight.

How It Works

Cyclosporine suppresses the immune system and may slow the rapid growth of skin cells.

Why It Is Used

Cyclosporine is used to treat severe plaque psoriasis that has not improved with the use of methotrexate. It is very rarely used.

Cyclosporine should not be used by pregnant women or women of childbearing age.

How Well It Works

Cyclosporine is effective in clearing psoriasis and may help prevent relapse (flare-ups).1

Side Effects

Side effects of cyclosporine include:

  • Suppression of the immune system.
  • Kidney problems.
  • High blood pressure.
  • Nonmelanoma skin cancer.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

The safety of long-term treatment is not known.

Cyclosporine is not usually used to treat severe psoriasis in people who have human immunodeficiency virus (HIV) infection. Drugs that suppress the immune system are avoided in people with impaired immune systems.

Complete the new medication information form (PDF)Click here to view a form.(What is a PDF document?) to help you understand this medication.

References

Citations

  1. Naldi L, Rzany B (2004). Chronic plaque psoriasis. Clinical Evidence (12): 1–5.

Credits

Author Shannon Erstad, MBA/MPH
Author Ralph Poore
Editor Kathleen M. Ariss, MS
Associate Editor Michele Cronen
Primary Medical Reviewer Patrice Burgess, MD
- Family Medicine
Primary Medical Reviewer Kathleen Romito, MD
- Family Medicine
Specialist Medical Reviewer Alexander H. Murray, MD, FRCPC
- Dermatology
Last Updated January 6, 2006
Last Updated: 01/06/2006

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This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information. For more information, click here. Privacy Policy. How this information was developed.

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