| WHO* Dysplasia System | Cervical Intraepithelial Neoplasia (CIN) | The Bethesda System |
|---|---|---|
|
Normal (benign) |
Normal (benign) |
Normal (benign) |
|
Benign with inflammation |
Not reported in CIN |
Infection and atypical squamous cells (ASC), which includes ASC of undetermined significance (ASC-US) and ASC that cannot exclude high-grade squamous intraepithelial lesions (HSIL) (ASC-H) |
|
Dysplasia (mild) |
CIN 1 |
Low-grade squamous intraepithelial lesions (LSIL) |
|
Dysplasia (moderate to severe) |
CIN 2, CIN 3 |
High-grade squamous intraepithelial lesions (HSIL) |
|
Carcinoma in situ |
CIN 3 |
High-grade squamous intraepithelial lesions (HSIL) |
|
Invasive cancer |
Invasive cancer |
Squamous cell cancer |
* World Health Organization
Credits
| Author | Shannon Erstad, MBA/MPH |
| Editor | Kathleen M. Ariss, MS |
| Associate Editor | Denele Ivins |
| Associate Editor | Pat Truman |
| Primary Medical Reviewer | Joy Melnikow, MD, MPH - Family Medicine |
| Specialist Medical Reviewer | Barbara S. Apgar, MD, MS - Family Medicine, Women's Health |
| Specialist Medical Reviewer | Ross Berkowitz, MD - Obstetrics and Gynecology |
| Last Updated | January 12, 2007 |
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