Who is affected by peptic ulcer disease

Provided by: Healthwise
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About 1 out of every 10 people in Europe and North America will have a peptic ulcer at some time.1 Ulcers can occur at any age, but they are rare in children. Children who do have ulcers are more likely to have duodenal, rather than gastric, ulcers.

Peptic ulcer disease tends to occur in people who are also infected with Helicobacter pylori (H. pylori) bacteria or who use nonsteroidal anti-inflammatory drugs (NSAIDs).

  • About 1 out of 10 people who are infected with H. pylori develop peptic ulcer disease.2
  • Similarly, about 1 out of 10 people who use high doses of NSAIDs, such as people who have rheumatoid arthritis or osteoarthritis, develop peptic ulcer disease and the problems caused by ulcers, such as bleeding and perforation.3

References

Citations

  1. Cryer B, Spechler SJ (2006). Peptic ulcer disease. In M Feldman et al., eds., Sleisenger and Fordtran's Gastrointestinal and Liver Disease, 8th ed., vol. 1, pp. 1089–1110. Philadelphia: Saunders Elsevier.

  2. Feldman M, Le MS (2007). Peptic ulcer diseases. In DC Dale, DD Federman, eds., ACP Medicine, section 4, chap. 2. New York: WebMD.

  3. Lanza FL, et al. (1998). A guideline for the treatment and prevention of NSAID-induced ulcers. American Journal of Gastroenterology, 93(11): 2037–2046.

Credits

Author Monica Rhodes
Editor Kathleen M. Ariss, MS
Associate Editor Denele Ivins
Associate Editor Pat Truman
Primary Medical Reviewer Kathleen Romito, MD
- Family Medicine
Specialist Medical Reviewer Andrew H. Soll, MD
- Gastroenterology
Last Updated January 7, 2008
Last Updated: 01/07/2008

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This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information. For more information, click here. Privacy Policy. How this information was developed.

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