Hantavirus Pulmonary Syndrome (HPS) - Symptoms

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Symptoms

The first symptoms of hantavirus pulmonary syndrome (HPS) may resemble those of other common illnesses. HPS symptoms usually begin from 1 to 5 weeks after exposure to the virus and usually last 3 to 5 days (prodromal phase). Symptoms that almost always occur in the early stages of HPS are:

  • Sudden fever.
  • Muscle pain (myalgia), especially in the thighs, hips, and back, and sometimes in the shoulders.
  • Fatigue.

In the early stages of HPS, about one-half of the people also develop:

  • Headache.
  • Chills.
  • Nausea and vomiting.
  • Diarrhea.
  • Abdominal pain.
  • General feeling of being ill (malaise).
  • Dizziness and lightheadedness.

Other, less common symptoms of HPS that may occur include:

  • Joint pain.
  • Chest pain.
  • Sweating.

About 4 to 10 days after the initial symptoms appear, late symptoms usually develop, including:

  • Shortness of breath.
  • Coughing.
  • Rapid heartbeat and rapid breathing, indicating fluid buildup in the lungs (pulmonary edema).

Once these symptoms develop, a person's condition rapidly deteriorates, and hospitalization within 24 hours often is needed. Even people with mild cases of the infection need to be treated in a hospital.

HPS may be mistaken for other conditions with similar symptoms, such as the flu or pneumonia.

Author: Ralph Poore
Medical Review:Kathleen Romito, MD - Family Medicine
Pierre Rollin, MD - Center's for Disease Control and Prevention
Last Updated: 03/28/2006

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