Gabapentin for epilepsy

Provided by: Healthwise
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Examples

Brand Name Chemical Name
Neurontin gabapentin

Gabapentin requires several daily doses and comes in capsules and pills.

How It Works

It is not known exactly how gabapentin prevents seizures.

Why It Is Used

Gabapentin may be used alone or combined with other antiepileptic medicines to control partial seizures in adults and in children age 3 and older.

How Well It Works

People taking gabapentin in addition to other antiepileptic medicines may have fewer seizures.1 Although it is not as effective as other new epilepsy drugs, it may have fewer side effects. Gabapentin has not been shown to be effective for treating primary generalized seizures or childhood absence seizures.

Side Effects

Gabapentin is a well-tolerated drug that usually causes only mild side effects. These often go away within 1 to 2 weeks and include:

  • Dizziness.
  • Drowsiness and fatigue.
  • Headache.
  • Weight gain.
  • Foot swelling.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Cost

Gabapentin is expensive, but a generic version is now available.

Drug interactions

Many medicines for epilepsy can interact with other medicines you may be taking. This means that your epilepsy medicine may not work as well, or it may affect the way another medicine you are taking works. Some of these interactions can be dangerous. It is important to tell you doctor about all the medicines, herbal pills, and dietary supplements you are taking.

Risk of birth defects

All medicines for epilepsy have some risk of birth defects. But the risk of birth defects needs to be carefully compared to other risks to the baby if the mother stops taking her epilepsy medicine. If you are thinking about becoming pregnant, it is important to plan ahead and talk with your doctor about the benefits and risks of taking epilepsy medicine during your pregnancy. It you are already pregnant, it is not too late. The best thing to do is talk to your doctor about your pregnancy before you make any changes to the medicines you are taking.

Other concerns

For some people, gabapentin may produce side effects or carry risks that are not fully known yet. Report any unexpected side effects or problems to your doctor.

It may take time and careful, controlled adjustments by you and your doctor to find the combination, schedule, and dosing of medicine to best manage your epilepsy. The goal is to prevent seizures while causing as few unwanted side effects as possible. After the most effective medicine program is determined, it is important that you follow it exactly as prescribed.

Complete the new medication information form (PDF)Click here to view a form.(What is a PDF document?) to help you understand this medication.

References

Citations

  1. Jarrar RG, Buchhalter JR (2003). Therapeutics in pediatric epilepsy, part 1: The new antiepileptic drugs and the ketogenic diet. Mayo Clinical Procedures, 78(3): 359–370.

Credits

Author Monica Rhodes
Editor Kathleen M. Ariss, MS
Associate Editor Pat Truman
Primary Medical Reviewer Michael J. Sexton, MD
- Pediatrics
Specialist Medical Reviewer Theresa O'Young, PharmD
- Clinical Pharmacist
Specialist Medical Reviewer Steven C. Schachter, MD
- Neurology
Last Updated October 29, 2007
Last Updated: 10/29/2007

© 1995-2007, Healthwise, Incorporated, P.O. Box 1989, Boise, ID 83701. ALL RIGHTS RESERVED.

This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information. For more information, click here. Privacy Policy. How this information was developed.

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