Stopping medication for epilepsy

It is easy to understand people's reasons for wanting to stop medicine—side effects and drug toxicity, the cost and inconvenience of medicine, and, for women who want to have children, the increased risk of birth defects associated with some epilepsy medicines.

If you have not had a seizure in several years, you may want to discuss with your doctor the possibility of stopping treatment with medicine. You and your doctor will need to weigh the benefits of stopping treatment against the risk that your seizures may return.

You have a lower risk of having a seizure after stopping medicine if:

• You have not had a seizure in 2 years or more.
• You have only one type of seizure (except myoclonic seizures, which usually require lifelong treatment).
• You developed epilepsy as a child or teenager.
• You had only a few seizures before starting treatment.
• Your seizures were easy to control with initial drug therapy using only one medicine.
• Your electroencephalogram (EEG) is consistently normal.
• Brain scans (MRI or CT scan) do not show any obvious abnormalities or structural brain disease.
• You have normal intelligence.
• You have a type of epilepsy that tends to go away (remit), such as benign focal childhood epilepsy.

Usually, medicine is reduced slowly over 2 to 6 months. Talk with your doctor about whether or not you should drive—and if not, for how long—after you begin withdrawing the medicine. You are at highest risk for a seizure during this time. Most relapses tend to happen in the first year after you stop taking medicine, if they are going to happen at all.¹

Do not reduce your medicine dosage or stop taking your medicine without first consulting your doctor. Even if you have not had a seizure in several years while on medicine, stopping treatment may not be a good option for you.