Atypical squamous cells (ASC) of the cervix

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Atypical squamous cells (ASC) are abnormal cells found on a Pap test, but the reason for the abnormalities is not known. The causes of ASC include infection or inflammation.

ASC is further classified as:

  • ASC of undetermined significance (ASC-US).
  • ASC but cannot exclude high-grade squamous intraepithelial lesion (HSIL) (ASC-H).

If you have ASC-US abnormalities, your health professional will probably recommend watchful waiting or human papillomavirus (HPV) testing. ASC-H abnormalities have a higher risk of being identified as more severe changes and are evaluated with colposcopy.

Credits

Author Shannon Erstad, MBA/MPH
Editor Kathleen M. Ariss, MS
Associate Editor Denele Ivins
Associate Editor Pat Truman
Primary Medical Reviewer Joy Melnikow, MD, MPH
- Family Medicine
Specialist Medical Reviewer Barbara S. Apgar, MD, MS
- Family Medicine, Women's Health
Specialist Medical Reviewer Ross Berkowitz, MD
- Obstetrics and Gynecology
Last Updated January 12, 2007
Last Updated: 01/12/2007

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